Video above: CDC document warns delta variant appears to spread as easily as chickenpoxDr. Anthony Fauci warned Sunday that more "pain and suffering" is on the horizon as COVID-19 cases climb again and officials plead with unvaccinated Americans to get their shots.Fauci, the nation's top infectious disease expert, also said he doesn't foresee additional lockdowns in the U.S. because he believes enough people are vaccinated to avoid a recurrence of last winter. However, he said not enough are inoculated to "crush the outbreak" at this point.Fauci's warning comes days after the Centers for Disease Control and Prevention changed course to recommend that even vaccinated people return to wearing masks indoors in parts of the U.S. where the delta variant is fueling infection surges. With the switch, federal health officials have cited studies showing vaccinated people can spread the virus to others.Most new infections in the U.S. continue to be among unvaccinated people. So-called breakthrough infections can occur in vaccinated people, and though the vast majority of those cause mild or no symptoms, the research shows they can carry about the same amount of the coronavirus as those who did not get the shots."So we're looking, not, I believe, to lockdown, but we're looking to some pain and suffering in the future because we're seeing the cases go up, which is the reason why we keep saying over and over again, the solution to this is get vaccinated and this would not be happening," Fauci said on ABC.According to data through July 30 from Johns Hopkins University, the seven-day rolling average for daily new cases in the U.S. rose from 30,887 on July 16 to 77,827 on July 30. The seven-day rolling average for the country's daily new deaths rose over the same period from 253 on July 16 to 358 on July 30, though death reports generally lag weeks after infections and even longer after hospitalizations. Currently, 58% of Americans 12 years and older are fully vaccinated, according to the CDC's data tracker.However, people are "getting the message" and more are rolling up their sleeves amid the threat of the delta variant, according to the director of the National Institutes of Health. Dr. Francis Collins said on CNN's "State of the Union" that vaccinations are up 56% in the U.S. in the last two weeks. Louisiana, which has the most new cases per capita among states in the past 14 days, has seen vaccinations up threefold over that period, Collins said."That's what desperately needs to happen if we are going to get this delta variant put back in its place, because right now it's having a pretty big party in the middle of the country," Collins said. Collins also said that even with the prevalence of the delta variant, the shots are working "extremely well" and reduce a person's risk of serious illness and hospitalization "25-fold." The guidance for vaccinated people to start wearing masks indoors again in certain places with worsening outbreaks, he said, is mostly meant to protect unvaccinated and immunocompromised people.The CDC has also recommended indoor mask-wearing for all teachers, staff, students and visitors at schools nationwide, regardless of vaccination status.

Countries around the world are entering new lockdowns as the coronavirus Delta variant continues to spread. Australia, Bangladesh, Germany, and South Africa are the latest in a string of nations to put new restrictions in place to try and curb the strain, per The Washington Post.Even as the U.S. population inches closer to halfway fully vaccinated, the World Health Organization is urging people not to throw caution to the wind. The Delta variant has already shown different mutations and a faster transmission rate than other strains, and experts are continually learning more about it. The WHO has been tracking COVID-19 variants since the beginning of the pandemic, and the Delta variant has been elevated into a "variant of concern" because it's a more contagious strain. Here's everything you need to know about the Delta variant — and how to protect yourself and others. What is the Delta variant?The WHO recently said that Delta is becoming the dominant COVID-19 variant worldwide, per CNBC. While the strain was first found in India, it has now spread to 80 countries, and it targets the most vulnerable individuals (mostly in places with low vaccination rates), per The New York Times.There isn't enough research available yet to confirm reports that the Delta variant may cause more severe symptoms. But Delta is potentially "more lethal because it's more efficient in the way it transmits between humans and it will eventually find those vulnerable individuals," Dr. Mike Ryan, executive director of the WHO's health emergencies program, said last week. What is the Delta-plus variant?After the Delta variant surfaced, a newer "Delta-plus" variant was also identified in India. Not much is known about Delta-plus, since researchers haven't had much time to study it yet, but it's believed to also be highly transmissible (like the Delta variant), per Los Angeles Times. Dr. George Rutherford, an epidemiologist at the University of California, San Francisco, says "it sounds like just another variant that’s no better, no worse, than the regular Delta variant, and it’s a little unclear why everybody’s pushing on it. I don’t see that this is a big, big problem right now."Dr. Monica Gandhi, an infectious-diseases expert at UC San Francisco, told the Los Angeles Times that "I know it keeps on seeming like there’s more and more, and so it’s certainly understandable why people are like, 'Why doesn’t it stop?' Once you tamp down transmission, it really will stop accumulating these mutations... That is the reason why we want to, of course, have global vaccine equity: to stop transmission."Is the Delta variant already in the U.S.?Yes, the Delta variant has already arrived in America. In a White House briefing last Tuesday, Dr. Anthony Fauci from the National Institute of Health said that 20.6% of new coronavirus cases in the U.S. are due to the Delta variant, per NPR. The CDC continues to add to its interactive map of Delta variant cases in the U.S.: Based on the CDC map, Delta is most present in central and western states, including Colorado, Montana, Wyoming, and Nebraska – but California and Texas aren't far behind, per Fast Company."The Delta variant is currently the greatest threat in the U.S. to our attempt to eliminate COVID-19," Fauci said. He also explained that the number of cases that are caused by the Delta variant is doubling every two weeks, per NPR. "We have the tools, so let's use them and crush the outbreak," he said. Who is at risk for contracting the Delta variant?Experts say that people in places with low COVID-19 vaccination rates are among the most vulnerable populations. "There still are big portions of the country where the rates of vaccination are quite low," said Dr. Jeremy Luban, a virologist at the University of Massachusetts Medical School, per NPR. "This Delta variant is increasing in frequency — the speed at which it's increasing in frequency is greatest in those areas where vaccination rates are lowest." Justin Lessler, an epidemiologist at Johns Hopkins University, says experts are keeping an eye on the Delta variant."For the most part, it's a moderate resurgence," he said, per NPR. "We're not having massive epidemics at a national level, but we have this kind of continuation of the virus just sticking around and keeping us on our toes. And in specific places, there could be substantial epidemics still."What new guidelines have the WHO released about the Delta variant? On Friday, the WHO strongly advised fully vaccinated people to continue wearing masks, social distance six feet apart, and practice other COVID-19 safety measures, per CNBC. Dr. Mariangela Simao is the WHO assistant director-general for access to medicines and health products. During a news briefing, she said that fully vaccinated people should continue to be cautious."People cannot feel safe just because they had the two doses," she said. "They still need to protect themselves." She added that the "vaccine alone won't stop community transmission. People need to continue to use masks consistently, be in ventilated spaced, hand hygiene...the physical distance, avoid crowding. This still continues to be extremely important, even if you're vaccinated when you have a community transmission ongoing," per CNBC.Does the coronavirus vaccine protect against the Delta variant?Yes. Dr. Rochelle Walensky, the director of the Centers for Disease Control and Prevention, says that COVID-19 vaccines do protect against the Delta variant."We know our vaccines work against this variant," she said, per NPR. "However this variant represents a set of mutations that could lead to future mutations that evade our vaccines. And that's why it's more important than ever to get vaccinated now to stop the chain of infection, the chain of mutations that could lead to a more dangerous variant."A new study found that the Moderna vaccine did produce neutralizing antibodies for the Delta variant, plus a few others, per CNBC. However, it's important to note that the study was small, and the data hasn't been peer reviewed yet. Can I still get COVID-19 if I'm fully vaccinated?Yes, but the chances are very small. Any case contracted after an individual has already been fully vaccinated is considered a breakthrough case. And some Delta cases have already been labeled breakthrough cases, according to The Wall Street Journal. Breakthrough cases are to be expected because the vaccines aren't 100% foolproof against COVID-19, says Professor Ran Balicer, the chief innovation officer for Clalit, Israel’s largest health-management organization.The CDC stopped tracking all breakthrough cases back in May. But they aren't as serious as they might sound: "If you are fully vaccinated, you have a lot of protection," L.A. County Public Health Director Barbara Ferrer told the Los Angeles Times. "And for the very small numbers of people that may end up in fact with a breakthrough vaccination case, they really did not have serious illness."Dr. Fauci seconded that Delta breakthrough cases tend to be less serious."Importantly, the protection against severe disease resulting in hospitalization and death is over 90%, 93, 94%. So if you are vaccinated, you're going to be protected," he said in an interview with NPR. For more information, the WHO recently posted a Q&A session about the impacts COVID-19 variants may have on vaccines' effectiveness on its Instagram. Will I need a vaccine booster shot?Possibly. Some experts are beginning to consider vaccine booster shots as one defense against the Delta variant, per Nasdaq. They're studying whether people who received Johnson & Johnson's one-dose vaccine might need booster shots of the Pfizer/BioNTech or Moderna mRNA-based vaccines in order to protect themselves. A few experts have already gotten booster shots, just to be safe, even though only preliminary data exists on whether combining different vaccines is safe and effective. Dr. Peter Hotez from Baylor College of Medicine tweeted that getting a J&J dose on top of a Pfizer or Moderna dose could offer better protection, but further guidance was necessary."In the phase 1-2 data, two doses of J&J gave higher virus neutralizing antibodies than a single dose, and therefore might be better and broader protection against variants?" Hotez wrote. "Or a single dose J&J followed by mRNA, but we need data and CDC-FDA guidance."Johnson & Johnson said it is currently testing whether people's immune response from its vaccine could fight back against the Delta variant, but no data is available yet, per Nasdaq.

Countries around the world are entering new lockdowns as the coronavirus Delta variant continues to spread. Australia, Bangladesh, Germany, and South Africa are the latest in a string of nations to put new restrictions in place to try and curb the strain, per The Washington Post.

Even as the U.S. population inches closer to halfway fully vaccinated, the World Health Organization is urging people not to throw caution to the wind. The Delta variant has already shown different mutations and a faster transmission rate than other strains, and experts are continually learning more about it.

The WHO has been tracking COVID-19 variants since the beginning of the pandemic, and the Delta variant has been elevated into a "variant of concern" because it's a more contagious strain. Here's everything you need to know about the Delta variant — and how to protect yourself and others.

What is the Delta variant?

The WHO recently said that Delta is becoming the dominant COVID-19 variant worldwide, per CNBC. While the strain was first found in India, it has now spread to 80 countries, and it targets the most vulnerable individuals (mostly in places with low vaccination rates), per The New York Times.

There isn't enough research available yet to confirm reports that the Delta variant may cause more severe symptoms. But Delta is potentially "more lethal because it's more efficient in the way it transmits between humans and it will eventually find those vulnerable individuals," Dr. Mike Ryan, executive director of the WHO's health emergencies program, said last week.

What is the Delta-plus variant?

After the Delta variant surfaced, a newer "Delta-plus" variant was also identified in India.

Not much is known about Delta-plus, since researchers haven't had much time to study it yet, but it's believed to also be highly transmissible (like the Delta variant), per Los Angeles Times.

Dr. George Rutherford, an epidemiologist at the University of California, San Francisco, says "it sounds like just another variant that’s no better, no worse, than the regular Delta variant, and it’s a little unclear why everybody’s pushing on it. I don’t see that this is a big, big problem right now."

Dr. Monica Gandhi, an infectious-diseases expert at UC San Francisco, told the Los Angeles Times that "I know it keeps on seeming like there’s more and more, and so it’s certainly understandable why people are like, 'Why doesn’t it stop?' Once you tamp down transmission, it really will stop accumulating these mutations... That is the reason why we want to, of course, have global vaccine equity: to stop transmission."

Is the Delta variant already in the U.S.?

Yes, the Delta variant has already arrived in America. In a White House briefing last Tuesday, Dr. Anthony Fauci from the National Institute of Health said that 20.6% of new coronavirus cases in the U.S. are due to the Delta variant, per NPR.

The CDC continues to add to its interactive map of Delta variant cases in the U.S.:

Based on the CDC map, Delta is most present in central and western states, including Colorado, Montana, Wyoming, and Nebraska – but California and Texas aren't far behind, per Fast Company.

"The Delta variant is currently the greatest threat in the U.S. to our attempt to eliminate COVID-19," Fauci said. He also explained that the number of cases that are caused by the Delta variant is doubling every two weeks, per NPR.

"We have the tools, so let's use them and crush the outbreak," he said.

Who is at risk for contracting the Delta variant?

Experts say that people in places with low COVID-19 vaccination rates are among the most vulnerable populations. "There still are big portions of the country where the rates of vaccination are quite low," said Dr. Jeremy Luban, a virologist at the University of Massachusetts Medical School, per NPR. "This Delta variant is increasing in frequency — the speed at which it's increasing in frequency is greatest in those areas where vaccination rates are lowest."

Justin Lessler, an epidemiologist at Johns Hopkins University, says experts are keeping an eye on the Delta variant.

"For the most part, it's a moderate resurgence," he said, per NPR. "We're not having massive epidemics at a national level, but we have this kind of continuation of the virus just sticking around and keeping us on our toes. And in specific places, there could be substantial epidemics still."

What new guidelines have the WHO released about the Delta variant?

On Friday, the WHO strongly advised fully vaccinated people to continue wearing masks, social distance six feet apart, and practice other COVID-19 safety measures, per CNBC.

Dr. Mariangela Simao is the WHO assistant director-general for access to medicines and health products. During a news briefing, she said that fully vaccinated people should continue to be cautious.

"People cannot feel safe just because they had the two doses," she said. "They still need to protect themselves."

She added that the "vaccine alone won't stop community transmission. People need to continue to use masks consistently, be in ventilated spaced, hand hygiene...the physical distance, avoid crowding. This still continues to be extremely important, even if you're vaccinated when you have a community transmission ongoing," per CNBC.

Does the coronavirus vaccine protect against the Delta variant?

Yes. Dr. Rochelle Walensky, the director of the Centers for Disease Control and Prevention, says that COVID-19 vaccines do protect against the Delta variant.

"We know our vaccines work against this variant," she said, per NPR. "However this variant represents a set of mutations that could lead to future mutations that evade our vaccines. And that's why it's more important than ever to get vaccinated now to stop the chain of infection, the chain of mutations that could lead to a more dangerous variant."

A new study found that the Moderna vaccine did produce neutralizing antibodies for the Delta variant, plus a few others, per CNBC. However, it's important to note that the study was small, and the data hasn't been peer reviewed yet.

Can I still get COVID-19 if I'm fully vaccinated?

Yes, but the chances are very small. Any case contracted after an individual has already been fully vaccinated is considered a breakthrough case. And some Delta cases have already been labeled breakthrough cases, according to The Wall Street Journal.

Breakthrough cases are to be expected because the vaccines aren't 100% foolproof against COVID-19, says Professor Ran Balicer, the chief innovation officer for Clalit, Israel’s largest health-management organization.

The CDC stopped tracking all breakthrough cases back in May. But they aren't as serious as they might sound: "If you are fully vaccinated, you have a lot of protection," L.A. County Public Health Director Barbara Ferrer told the Los Angeles Times. "And for the very small numbers of people that may end up in fact with a breakthrough vaccination case, they really did not have serious illness."

Dr. Fauci seconded that Delta breakthrough cases tend to be less serious.

"Importantly, the protection against severe disease resulting in hospitalization and death is over 90%, 93, 94%. So if you are vaccinated, you're going to be protected," he said in an interview with NPR.

For more information, the WHO recently posted a Q&A session about the impacts COVID-19 variants may have on vaccines' effectiveness on its Instagram.

Will I need a vaccine booster shot?

Possibly. Some experts are beginning to consider vaccine booster shots as one defense against the Delta variant, per Nasdaq. They're studying whether people who received Johnson & Johnson's one-dose vaccine might need booster shots of the Pfizer/BioNTech or Moderna mRNA-based vaccines in order to protect themselves.

A few experts have already gotten booster shots, just to be safe, even though only preliminary data exists on whether combining different vaccines is safe and effective. Dr. Peter Hotez from Baylor College of Medicine tweeted that getting a J&J dose on top of a Pfizer or Moderna dose could offer better protection, but further guidance was necessary.

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In the phase 1-2 data, two doses of JnJ gave higher virus neutralizing antibodies than a single dose, and therefore might be better and broader protection against variants? Or a single dose JnJ followed by mRNA, but we need data and CDC-FDA guidance

— Prof Peter Hotez MD PhD (@PeterHotez) June 25, 2021

"In the phase 1-2 data, two doses of J&J gave higher virus neutralizing antibodies than a single dose, and therefore might be better and broader protection against variants?" Hotez wrote. "Or a single dose J&J followed by mRNA, but we need data and CDC-FDA guidance."

Johnson & Johnson said it is currently testing whether people's immune response from its vaccine could fight back against the Delta variant, but no data is available yet, per Nasdaq.