The Centers for Disease Control (CDC) says health care providers in several regions are seeing young patients with enterovirus D68 (EV-D68).

The virus has been associated with neurologic complications, albeit rare, involving limb weakness, primarily affecting children, the CDC stated.

An alert has been sent out to providers to watch out for EV-D68. Symptoms include cough, shortness of breath, and wheezing. Fever was reported in approximately half of the known cases, according to the CDC.

"Children with a history of asthma or reactive airway disease may be more likely to require medical care, though children without a known history of asthma can also present with severe illness," the CDC said.

The peak season for EV-D68 is late summer and early fall, the CDC warns.

To help protect against the virus, people are encouraged to routinely wash their hands and avoid close contact with people who are sick.

There is currently no vaccine or specific treatment for EV-D68.

YADKIN COUNTY, N.C. —

Forty-five middle school students from North Carolina got sick Monday afternoon for an unknown reason.

Sixth graders at Starmount Middle School in Yadkin County began complaining about feeling nauseous with headaches. Some students had thrown up.

Only sixth graders were affected, neither seventh nor eighth-graders reported becoming sick, according to the Yadkin County Schools superintendent.

In response to the mysterious epidemic, the school did a shelter in place to keep unaffected students away from the others that were ill.

"I understand parents were nervous and upset. No messaging went out [from the school] because I can tell you, I saw first hand, administration and front office staff were focused on helping students. That's first priority," Yadkin County Schools Superintendent Todd Martin said.

First responders came to the school to help and check the students out.

Yadkin County Schools and the Yadkin County Health Department are investigating the strange illness that affected the 45 students.

Most of the affected students returned to school the following Tuesday.

There were rumors of a CO2 leak, but Martin said that was ruled out.

Officials are investigating possible food poisoning, but this has not been confirmed as the cause of the sickness.

Parents should hear from the school Monday evening.

This is a developing story, check back for more updates.

As winter approaches, schools are preparing for a number of illnesses in addition to COVID-19.

“Since we especially didn't see a flu season last season, we’re on the ready for a potentially severe influenza season. Particularly because of circulation of COVID,” said Dr. Sara Saporta-Keating, a pediatric infectious disease specialist at Children’s Hospital Colorado, Colorado Springs.

But schools are more prepared than before after balancing education with pandemic safety.

“Push this button and it will turn on -- like this -- and if it's green that means you’re good,” 7-year-old Lexi Ansardi said. She is a second grader at Centennial Elementary School. Every morning, she checks her temperature and with the help of her mom, Ann. She can keep track of her health on an app.

“I am concerned about flu, COVID of course, but this app, it actually gives you ideas about what might be happening with your student depending on the fever,” Ann Ansardi said. “It really gives the parents a way of knowing what's going on in the building in terms of health.”

Most families at this elementary school are using these thermometers consistently through something called the FLUency program -- a free program to reduce the spread of illness in schools through health technology company Kinsa.

“It is an initiative to stop the spread of illness in classrooms to help the entire community know more about what symptoms and illnesses are going around,” Nita Nehru, vice president of communications at Kinsa, said.

“On a population level, we’re able to understand where symptoms are starting and how fast they are spreading,” she explained. Nehru said the app provides anonymous, aggregated information on what symptoms and illnesses are going around in any given classroom, school, or community.

“It’s a way of reducing some of your clinic load for school nurses,” she said. “Schools, right now, are really acting as that first line of defense, and that’s just not sustainable.”

With the app, it’s easier for schools to see multiple cases of illness at the onset, leading to more accurate decisions about when to temporarily go to remote learning or distance kids more.

“Once you put the app in, you have a running tally of what your illness and your child has looked like…and you take that right to the doctor with you,” Ann Ansardi said.

Pediatric doctors are prepared for what they could see this season.

“What we have been doing to mitigate COVID can also be helpful for mitigating flu. So the first thing is good hand washing, another thing is making sure that if you're ill you don't go to work or school. And then getting vaccinated if you're able to against the flu particularly, as well as COVID,” Dr. Saporta-Keating said. She said she is also seeing higher rates of more common respiratory viruses.

“Usually we see those later in the season, so really it's important for schools again to be making sure they understand what’s going on,” she explained.

Centennial Elementary School principal Kim Noyes said the FLUency program has been a huge help in detecting potential outbreaks.

“The vast majority of our school and our families are using the digital thermometer and I think that has led to very low incidents of illness in our school,” she said.

All it takes is a little participation from students and families.

“If one person is sick, a whole bunch of other people can get sick. So if you're sick, this helps,” Lexi said.

As we move into the winter months, Noyes feels prepared. “We can't control the future but we can take every single preventative step possible,” she said.