CINCINNATI (AP) — Paul Goldschmidt gave St. Louis the lead with his second homer of the game as the Cardinals tightened up the NL wild-card race with a 5-4 win over the Cincinnati Reds in the opener of a doubleheader on Wednesday.

The Reds entered the day tied with San Diego for the second NL wild card, 2 1/2 games of St. Louis and Philadelphia.

The Cardinals trailed 4-3 before Goldschmidt drove his third homer of the series into the last section of seats in deep right-center with Tommy Edman on first base.

The doubleheader was scheduled after Tuesday’s game was postponed because of rain.

The Reds have lost four straight for the first time since dropping four in a row from July 16-19.

The Cardinals bashed three homers among their 12 hits off Wade Miley (11-5), both season highs for the left-hander. Miley gave up five runs with one walk and two strikeouts in four innings for his first loss in 16 starts since coming off the injured list on May 30.

Reliever Génesis Cabrera (3-5) pitched two scoreless innings for St. Louis. Giovanny Gallegos pitched the seventh for his fourth save and second in the Cardinals’ last two games, both against Cincinnati.

The Reds scored three runs in the third inning, equaling the total from their previous three games combined. Miley drove in two with an opposite-field double to left.

Goldschmidt, the game’s second batter, launched a changeup off the ribbon message board atop the center field batter’s eye. He now has 24 homers this season.

St. Louis right-hander Miles Mikolas lasted only three innings in his third start since coming off the injured list on August 20. He allowed five hits and four runs with one walk and three strikeouts.

TRAINER’S ROOM

Cardinals: RHP Ryan Helsley (right elbow stress reaction) was transferred to the 60-day injured list. He has been out since August 17.

Reds: OF Jesse Winker, on the 10-day injured list since August 16 with an intercostal strain, started swinging a bat on Tuesday, manager David Bell said.

UP NEXT

Cardinals: Begin a three-game series at the NL Central-leading Brewers on Friday night with RHP Adam Wainwright (13-7, 2.95 ERA) on the mound. St. Louis has won each of Wainwright’s last eight starts at Milwaukee since a 4-3 loss on July 18, 2012.

Reds: RHP Vladimir Gutierrez (9-5, 4.03), Friday’s starter against Detroit, allowed seven hits and five runs in a season-low three innings in his last start on Saturday at Miami.

CINCINNATI (AP) — Mike Moustakas went 3 for 4 with three doubles and two RBIs in his return from the injured list to spark the Cincinnati Reds to a 10-0 rout of the Pittsburgh Pirates on Friday night.

Tucker Barnhart hit a three-run homer, Jesse Winker and Jonathan India each hit solo homers and the Reds moved within three games of the Padres for the second NL Wild Card spot.

For the sixth time this season, the Reds scored at least 10 runs for Wade Miley (9-4), who allowed only six hits through seven innings.

Pirates starter JT Brubaker (4-11) owned a 1.76 ERA in three previous starts against Cincinnati, but was hit hard on Friday.

Moustakas — who came off the IL on Friday after missing 68 games with a right heel contusion — had a two-run double in his first at-bat.

Barnhart’s three-run blast to right capped off a seven-run first inning.

Winker led off the second with his 22nd homer of the season. Moustakas doubled and scored on Kyle Farmer’s single and the Reds led 9-0 after two innings.

Moustakas is the first Reds batter with three doubles in a game since Jose Peraza did it on Aug. 15, 2018 against Cleveland.

India’s solo homer off Kyle Keller in the sixth capped the scoring. It was his fourth homer in seven games.

TRAINERS ROOM

Pirates: Outfielder Ben Gamel, who was scratched from Thursday’s start, was placed on the 10-day injured list with a right hamstring strain. First baseman Colin Moran (left wrist fracture) was reinstated from the 10-day IL.

Reds: Catcher Tyler Stephenson, who left Thursday’s game with a cramp, was available off the bench. RHP Lucas Sims (right elbow) completed his minor-league rehab and could be activated Sunday.

UP NEXT

The Pirates will start RHP Mitch Keller against Reds RHP Vladimir Gutierrez on Saturday. Keller is 0-2 with a 9.37 ERA and 17 earned runs allowed in 16 1/3 innings in four career starts against the Reds. Gutierrez will make his 13th career appearance, first against the Pirates.